Our DNA is subject to mutations on a daily basis. Why do most mutations that occur in the genome of organisms escape detection and not elicit a deleterious effect?

Please answer the following questions in a 200-word response minimum. Try your best to reference the text I will message you privately for how to access the text book.

Our DNA is subject to mutations on a daily basis. Why do most mutations that occur in the genome of organisms escape detection and not elicit a deleterious effect? Why does the child of someone with cancer not necessarily develop cancer?

How would you explain variations in chromosome number and gene arrangement that result in inheritable disorders?

Mutagenic activity, as detected by the Ames/ Salmonella test system can be used to discriminate whether an environmental effect is mutagenic or carcinogenic. How would you distinguish between a mutagen and a carcinogen?

It is very important in the process of Mitosis that each new daughter cell receive a complete copy of the parent cell’s DNA. If there is just one base left out this is called a mutation, and mutations can be helpful, harmful or neutral. However, you do not want that mutation being passed down to the offspring, if it is harmful. Therefore it is important to have each cell possess a complete unchanged copy of the original DNA so that you can protect the original blueprint. Do you know of any mutations that are “good”? Why are they good?

This is a simple question: If genetic mutations are common and occur naturally, why does everyone not develop cancer?

Why do you think gene regulation is more complex in a multicellular organism versus a single-celled organism? Why is it harder to study gene regulation in eukaryotes?


 

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